Best practice portal – evidence database

This database gives you access to the latest evidence on drug-related interventions. The information is based on systematic searches is updated regularly. To get started use the search boxes below. Click here for more information about the Evidence database (including methods).

List of Evidence Summaries
Title Area Substance Target group(s) or setting(s) Evidence rating
Buprenorphine substitution to retain patients in treatment Treatment opioids Beneficial
Family and school based programmes to prevent smoking Prevention tobacco families, school Beneficial
Combined opioid substitution treatment (OST) and needle and syringe programmes (NSP) to prevent HCV (and HIV) infection and reduce injecting risk behaviours Harm reduction opioids PWID – people who inject drugs Beneficial
School-based multicomponent positive psychology interventions on well-being and distress Prevention not-drug specific school Beneficial
Take-home naloxone (THN) to improve knowledge and attitude towards opioid overdose Harm reduction opioids PWID – people who inject drugs Beneficial
Needle and syringe programmes to prevent HCV and HIV infection and reduce injecting risk behaviours Harm reduction amphetamines, opioids PWID – people who inject drugs Beneficial
Opioid substitution therapy to reduce deaths in prison Harm reduction opioids prison Beneficial
Buprenorphine vs methadone substitution to retain patients in treatment Treatment opioids Beneficial
Opioid substitution treatment (with methadone) in prison to increase post-incarceration community treatment engagement Treatment opioids prison Beneficial
Permanent supportive housing to improve housing stability for vulnerably housed persons Social reintegration not-drug specific Beneficial
Take-home naloxone (THN) economic evaluation Harm reduction opioids PWID – people who inject drugs Beneficial
Psychosocial interventions with substitution treatment to retain patients in treatment Treatment opioids Likely to be beneficial
Police interventions in nightlife settings to reduce crime Prevention not-drug specific communities, law enforcement, partygoers/nightlife Likely to be beneficial
Pre- and post -exposure prophylaxis of HIV in prison to reduce HIV acquisition Harm reduction not-drug specific prison Likely to be beneficial
Technology-based interventions to reduce substance use in women Treatment pregnant women, women Likely to be beneficial
Pharmacological treatment for neonatal abstinence syndrome Treatment opioids Likely to be beneficial
Support groups combined with peer mentor training delivered to young people with parents or other family members who are substance users Prevention not-drug specific families, young people Likely to be beneficial
Emergency department-based opioid substitution treatment (OST) initiation Treatment opioids emergency department Likely to be beneficial
Pharmacological treatment of attention deficit hyperactivity disorder (ADHD) and substance use disorders Treatment co-morbidity dual-diagnosis patients Likely to be beneficial
Opioid substitution treatment (OST) for people dependent on pharmaceutical opioids Treatment opioids Likely to be beneficial
Police and law enforcement measures to increase responsible serving behaviours Prevention alcohol law enforcement, partygoers/nightlife Likely to be beneficial
Naloxone training and prescription to reduce opioid overdose mortality after release from prison Harm reduction opioids prison Likely to be beneficial
Interventions to increase knowledge and reduce risk of drugs-and-driving Prevention alcohol, cannabis young people Likely to be beneficial
mHealth (mobile/wearable device) to reduce craving and use in substance use disorders Treatment not-drug specific Likely to be beneficial
Integrated approaches to improve engagement and adherence to HCV treatment among PWID Treatment opioids PWID – people who inject drugs Likely to be beneficial
Naloxone to revert synthetic opioids overdose Harm reduction new psychoactive substances (NPS), opioids, prescription medicines emergency department, PWID – people who inject drugs Likely to be beneficial
Interventions that lead to the highest treatment retention for young adults Treatment alcohol, cannabis, opioids young people Likely to be beneficial
Naltrexone to retain people in treatment Treatment opioids Likely to be beneficial
Combined enforcement checks and management training to reduce under-age serving Prevention alcohol law enforcement, partygoers/nightlife Likely to be beneficial
Computer-based treatment programs to improve mental health and treatment outcomes Treatment co-morbidity dual-diagnosis patients Likely to be beneficial
Drug court programmes to reduce recidivism Social reintegration not-drug specific prison Likely to be beneficial
Psychostimulants to reduce stimulant use Treatment amphetamines, cocaine Likely to be beneficial
Opioid substitution treatment (OST) to improve anti-retro-viral treatment in HIV positive opioid users Harm reduction opioids PWID – people who inject drugs Likely to be beneficial
Police-based diversion measures to prevent criminal offending and decrease social costs Harm reduction not-drug specific law enforcement Likely to be beneficial
Multi-substance interventions addressing tobacco and/or cannabis to reduce use Treatment cannabis, tobacco Likely to be beneficial
Psychosocial interventions for family members affected by substance abuse Treatment not-drug specific families Likely to be beneficial
Manualised mindfulness-based programs for substance use disorders to reduce cravings Treatment not-drug specific Likely to be beneficial
Contingency management for patients with psychotic and substance use disorders Treatment not-drug specific dual-diagnosis patients Likely to be beneficial
Therapeutic communities in prison to reduce re-incarceration rates and drug misuse relapse Treatment opioids prison Likely to be beneficial
Outreach and education to reduce injecting risk behaviour Harm reduction amphetamines, opioids PWID – people who inject drugs Likely to be beneficial
Behavioural therapies to reduce use in adolescents Treatment not-drug specific young people Likely to be beneficial
Training for alcohol servers to reduce the level of patron’s intoxication Prevention alcohol partygoers/nightlife Likely to be beneficial
Continuity of care to improve post-release behavioural outcomes Treatment not-drug specific prison Likely to be beneficial
Comprehensive family-oriented prevention for cannabis use Prevention cannabis families, young people Likely to be beneficial
Pre-exposure prophylaxis of HIV in adults at high risk (PreP) to reduce HIV acquisition Harm reduction amphetamines, opioids PWID – people who inject drugs Likely to be beneficial
Continuing care to improve treatment outcomes Treatment not-drug specific Likely to be beneficial
Anti-tobacco multi-component community interventions Prevention tobacco communities Likely to be beneficial
Community interventions to reduce risky drinking Prevention alcohol, not-drug specific communities Likely to be beneficial
Multidimensional family therapy (MDFT) vs cognitive behavioral therapy (CBT) to reduce use Treatment cannabis families, young people Likely to be beneficial
Family-based prevention programs in preventing alcohol misuse in school-aged children up to 18 years of age Prevention alcohol communities, young people Likely to be beneficial

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